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KMID : 0382319880080010013
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Environmental Mutagens and Carcinogens
1988 Volume.8 No. 1 p.13 ~ p.21
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Effect of L-Ascorbic Acid on the Mutagenicity of Aflatoxin B1 in the Salmonella Assay System
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박건영
권미향/백형석/최홍식
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Abstract
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Mutagenic actions of aflatoxin B1 (AFB1) in the presence of various concentrations of L-ascorbIc acid (AA) in Salmonella typhimurium strains TA 100 and TA98 were studied. Spontaneous revertants per plate of the tester strains TA100 and TA98 were 121-125 and 25-30 with or without S9 mix, respectively. The negative controls used in the study did not show any mutagenesis in the tester strains. AFB1 revealed strong mutagenicity at the dose levels of 0.05, 0.1 and 0.25 mg/plate with metabolic activation system in both strains.
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KEYWORD
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